招生工作
导师介绍
彭倩倩
博士 副研究员 硕士生导师
人类表型组学研究组
研究方向：计算生物学、衰老与复杂疾病分析方法
电子邮件(E-mail)：pengqianqian@sinh.ac.cn
电话(Tel)：021-54920551
简历

2019.05-至　 今：中国科学院上海营养与健康研究所 副研究员
2015.11-2019.05：中国科学院上海生命科学研究院-马普计算生物学伙伴研究所 副研究员
2013.07-2015.11：中国科学院上海生命科学研究院-马普计算生物学伙伴研究所 助理研究员
2009.09-2013.01：复旦大学 遗传学博士
2006.09-2009.07：山东大学 流行病与卫生统计硕士
2002.09-2006.07：山东大学 统计学学士

研究内容

围绕衰老与复杂疾病，开发衰老量化新方法，依托大型人群队列数据、多组学技术探索衰老与疾病共病潜在的分子基础，建立衰老与疾病的风险预测模型。
1、器官衰老的非线性与异质性量化及共病机制解析
2、跨组学关联图谱及其在衰老与疾病解析中的应用
3、基于多组学的体质特征与代谢性疾病一因多效性解析与预测模型构建

代表性论文（#共同第一作者, *共同通讯作者）
  1. Peng Q#, Liu Y#, Huels A, Zhang C, Yu Y, Qiu W, Cai X, Zhao Y, Schikowski T, Merches K, Liu Y, Yang Y, Wang J, Zhao Y, Jin L, Zhang L, Krutmann J, Wang S. Genetic Variants in Telomerase Reverse Transcriptase Contribute to Solar Lentigines. J Invest Dermatol 2023 Jun;143(6):1062-1072
  2. Li B#, Kamarck ML#, Peng Q#, Lim FL, Keller A, Smeets MAM, Mainland JD, Wang S. From musk to body odor: Decoding olfaction through genetic variation. PLoS Genet 2022 Feb 3;18(2):e1009564
  3. Zhang M, Wu S, Du S, Qian W, Chen J, Qiao L, Yang Y, Tan J, Yuan Z, Peng Q, Liu Y, Navarro N, Tang K, Ruiz-Linares A, Wang J, Claes P, Jin L, Li J, Wang S. Genetic variants underlying differences in facial morphology in East Asian and European populations. Nat Genet 2022 Apr;54(4):403-411
  4. Li J, Glover JD, Zhang H, Peng M, Tan J, Mallick CB, Hou D, Yang Y, Wu S, Liu Y, Peng Q, Zheng SC, Crosse EI, Medvinsky A, Anderson RA, Brown H, Yuan Z, Zhou S, Xu Y, Kemp JP, Ho YYW, Loesch DZ, Wang L, Li Y, Tang S, Wu X, Walters RG, Lin K, Meng R, Lv J, Chernus JM, Neiswanger K, Feingold E, Evans DM, Medland SE, Martin NG, Weinberg SM, Marazita ML, Chen G, Chen Z, Zhou Y, Cheeseman M, Wang L, Jin L, Headon DJ, Wang S. Limb development genes underlie variation in human fingerprint patterns. Cell 2022 Jan 6;185(1):95-112
  5. Huang Y, Li D, Qiao L, Liu Y, Peng Q, Wu S, Zhang M, Yang Y, Tan J, Xu S, Jin L, Wang S, Tang K, Grünewald S. A genome-wide association study of facial morphology identifies novel genetic loci in Han Chinese. J Genet Genomics 2021 Mar 20;48(3):198-207
  6. Liu Y, Gao W, Koellmann C, Le Clerc S, Hüls A, Li B, Peng Q, Wu S, Ding A, Yang Y, Jin L, Krutmann J, Schikowski T, Zagury JF, Wang S. Genome-wide scan identified genetic variants associated with skin aging in a Chinese female population. J Dermatol Sci 2019 Oct;96(1):42-49
  7. Wu S, Zhang M, Yang X, Peng F, Zhang J, Tan J, Yang Y, Wang L, Hu Y, Peng Q, Li J, Liu Y, Guan Y, Chen C, Hamer MA, Nijsten T, Zeng C, Adhikari K, Gallo C, Poletti G, Schuler-Faccini L, Bortolini MC, Canizales-Quinteros S, Rothhammer F, Bedoya G, González-José R, Li H, Krutmann J, Liu F, Kayser M, Ruiz-Linares A, Tang K, Xu S, Zhang L, Jin L, Wang S. Genome-wide association studies and CRISPR/Cas9-mediated gene editing identify regulatory variants influencing eyebrow thickness in humans. PLoS Genet 2018 Sep 24;14(9):e1007640
  8. Peng Q, Li J, Tan J, Yang Y, Zhang M, Wu S, Liu Y, Zhang J, Qin P, Guan Y, Jiao Y, Zhang Z, Sabeti PC, Tang K, Xu S, Jin L, Wang S. EDARV370A associated facial characteristics in Uyghur population revealing further pleiotropic effects. Hum Genet 2016 Jan;135(1):99-108
  9. Wu S, Tan J, Yang Y, Peng Q, Zhang M, Li J, Lu D, Liu Y, Lou H, Feng Q, Lu Y, Guan Y, Zhang Z, Jiao Y, Sabeti P, Krutmann J, Tang K, Jin L, Xu S, Wang S. Genome-wide scans reveal variants at EDAR predominantly affecting hair straightness in Han Chinese and Uyghur populations. Hum Genet 2016 Nov;135(11):1279-1286
  10. Tan J#, Peng Q#, Li J, Guan Y, Zhang L, Jiao Y, Yang Y, Wang S, Jin L. Characteristics of dental morphology in the Xinjiang Uyghurs and correlation with the EDARV370A variant. Sci China Life Sci 2014 May;57(5):510-518
  11. Zhao JY, Qiao B, Duan WY, Gong XH, Peng QQ, Jiang SS, Lu CQ, Chen YJ, Shen HB, Huang GY, Jin L, Wang HY. Genetic variants reducing MTR gene expression increase the risk of congenital heart disease in Han Chinese populations. Eur Heart J 2014 Mar;35(11):733-742
  12. Lin Q#, Peng Q#, Yao F, Pan XF, Xiong LW, Wang Y, Geng JF, Feng JX, Han BH, Bao GL, Yang Y, Wang X, Jin L, Guo W, Wang JC. A classification method based on principal components of SELDI spectra to diagnose of lung adenocarcinoma. PLoS One 2012;7(3):e34457
  13. Peng Q#, Zhao J, Xue F. A gene-based method for detecting gene-gene co-association in a case-control association study. Eur J Hum Genet 2010 May;18(5):582-7
  14. Peng Q#, Zhao J, Xue F. PCA-based bootstrap confidence interval tests for gene-disease association involving multiple SNPs. BMC Genet 2010 Jan 26;11:6